LDgenX

Explore LDgenX

Ask for a quote

Evolutionary Applications · 2021

Epigenomic modifications induced by hatchery rearing persist in germ line cells of adult salmon after their oceanic migration

Leitwein M, Laporte M, Le Luyer J, Mohns K, Normandeau E, Withler R, Bernatchez L

In coho salmon, methylation differences associated with the early rearing environment are found in the germ cells of adults after their ocean migration. This persistence raises questions about the possible long-term effects of rearing and a possible transmission across generations.

The question
Are epigenetic signatures of early rearing still present in the germ cells of adults?
The approach
Whole-genome bisulfite sequencing of the milt of adult salmon of wild or hatchery origin, in two rivers.
What the article brings
Differentially methylated regions are kept until adults return to spawn.
The limits
The persistence of these marks in germ cells does not, on its own, demonstrate their transmission to offspring.

Figures from the article

Figure 2, Epigenomic modifications induced by hatchery rearing persist in germ line cells of adult salmon after their oceanic migrationFigure (opens in a new tab)
Figure 2. Circle plot showing the 183 differentially methylated regions (DMRs) between hatchery and wild adult fish in milt tissue Only the chromosomes(n = 30) containing DMRs are represented. Red points indicate hypermethylated and blue points hypomethylated DMRs for the hatchery fish. The overlapping transcripts are represented and details can be found in Table S4 . Chromosomes for which db‐RDA were significant are presented in grayOriginal caption. Leitwein M et al. (2021), Evolutionary Applications. CC BY 4.0

Let’s discuss your project

Your question. Our next starting point.

A project in biodiversity, genomics or bioinformatics? Describe your needs to receive a proposal, or book a first conversation with our scientific team.

Or write to us: info@ldgenx.fr